- 21c Museum Hotel Durham
- Aloft Durham Downtown
- Arrowhead Inn
- Candlewood Suites Durham-Rtp
- Comfort Inn & Suites Durham Near Duke University
- Comfort Inn Research Triangle Park
- Comfort Inn University Durham - Chapel Hill
- Courtyard Durham Near Duke University/Downtown
- Days Inn by Wyndham Durham/Near Duke University
- DoubleTree Suites by Hilton Raleigh - Durham
- DoubleTree by Hilton Raleigh - Durham Airport at Research Triangle Park
- Durham Marriott City Center
- Econo Lodge Research Triangle Park
- Extended Stay America - Raleigh-Research Triangle Park-Hwy55
- Extended Stay America Select Suites - Durham - University
- Extended Stay America Select Suites - Durham - University - Ivy Creek Blvd
- Extended Stay America Select Suites - Raleigh - RTP - 4919 Miami Blvd.
- Extended Stay America Select Suites - Raleigh - Rtp - 4610 Miami Blvd
- Fairfield Inn & Suites by Marriott Durham Southpoint
- Hampton Inn & Suites Durham/North I-85
- Hilton Durham near Duke University
- Hilton Garden Inn Durham Southpoint
- Hilton Garden Inn Durham/University Medical Center
- Hilton Garden Inn Raleigh-Durham/Research Triangle Park
- Holiday Inn Express & Suites Raleigh Durham Airport At Rtp, An IHG Hotel
- Holiday Inn Express Durham
- Homewood Suites by Hilton Durham-Chapel Hill / I-40
- Homewood Suites by Hilton Raleigh - Durham AP/Research Triangle
- Hyatt Place Durham Southpoint
- La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint
- La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill
- Marriott Raleigh Durham Research Triangle Park
- Millennium Durham
- Red Roof Inn Chapel Hill - UNC
- Red Roof Inn Durham - Duke Univ Medical Center
- Red Roof Inn Durham - Triangle Park
- Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
- Sleep Inn Raleigh Durham Airport
- SpringHill Suites by Marriott Durham Chapel Hill
- SpringHill Suites by Marriott Raleigh-Durham Airport/Research Triangle Park
- Staybridge Suites Durham-Chapel Hill-Rtp
- Super 8 by Wyndham Durham/University Area NC
- The Durham Hotel
- University Inn Duke
- Unscripted Durham
- Washington Duke Inn & Golf Club
- Wingate by Wyndham Raleigh Durham / Airport